Outcomes In The Ischemia Trial Based On Coronary Artery
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Results: The interim ISCHEMIA trial findings align with previous evidence where CABG reduces the long-term risks of myocardial infarction and mortality in advanced coronary
Atherosclerosis quantification and cardiovascular risk: the ISCHEMIA trial
Background: In the ISCHEMIA Trial, 5179 patients with stable coronary disease were randomized to initial invasive or conservative management. Methods: PCI was recommended with a
Abstract. Aims: We sought to assess the proportion of patients eligible for the ISCHEMIA trial and to compare the characteristics and outcomes of these patients with those without ISCHEMIA
We investigated the relationship between severity of CAD and ischemia and trial outcomes, overall and by management strategy. METHODS: In total, 5179 patients with
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The impact of moderate to severe ischemia in predicting outcomes cannot be studied in a trial where moderate to severe ischemia was one of the main inclusion criteria, due
coronary disease in the ISCHEMIA Trials Jonathan D. Newman Importance Biomarkers may improve prediction of cardiovascular events for patients with stable coronary artery disease
Complete coronary revascularization may be categorized as anatomic (revascularization of all lesions of at least 50% or 70% in vessels of at least 1.5 or 2 mm in diameter) or functional
Multivariable-adjusted outcomes of CR were examined in INV patients. Inverse probability weighted modeling was then performed to estimate the treatment effect had CR been achieved in all INV patients compared with CON
Ischemia Trial: Does the Cardiology Community Need to Pivot
Background: The ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) postulated that patients with stable coronary artery disease
Outcomes following initial invasive management (INV) with REV (PCI or CABG) versus initial conservative management (CON) with medical therapy alone were evaluated. Regression
Acute ischemic stroke is a leading global cause of death and disability. Intravenous thrombolysis was the first acute treatment developed for ischemic strokes. First with alteplase and now with
Reynolds HR, Shaw LJ, Min JK, et al. Outcomes in the ISCHEMIA Trial based on coronary artery disease and ischemia severity. Circulation. 2021;144:1024–38.
Abstract. BACKGROUND: Whether revascularisation (REV) improves outcomes in patients with three-vessel coronary artery disease (3V-CAD) is uncertain. AIMS: Our objective was to
BACKGROUND: There is heterogeneity in coronary artery disease (CAD) severity among individuals with severe aortic stenosis (AS), but whether this differentially
Velazquez EJ, Lee KL, Jones RH, et al. Coronary-artery bypass surgery in patients with ischemic cardiomyopathy. N Engl J Med 2016;374:1511–20. Crossref | PubMed; Schömig
Natural History of Patients with Ischemia and No Obstructive Coronary Artery Disease: The CIAO-ISCHEMIA Study. Circulation. 2021 Jun 01. DOI: 10.1161/CIRCULATIONAHA.120.046791.
Correction to: Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity Circulation . 2022 Jun 7;145(23):e1072. doi:
Chronic kidney disease (CKD) is a known predictor of cardiovascular events. 1, 2 Extent of coronary artery disease (CAD) portends a high-risk as these patients are far more
Purpose of Review This article presents a comprehensive review of coronary revascularization versus optimal medical therapy (OMT) in patients with severe ischemic left
Shown are survival curves from a Kaplan-Meier analysis. (A) Coronary artery disease stages based on percentage atheroma volume (PAV), survival free from primary
The present study included participants without prior coronary artery bypass grafting (CABG) from the ISCHEMIA trial with a core lab–evaluable CCTA. 18–21 In brief,
Reynolds HR, Shaw LJ, Min JK, Page CB, Berman DS, Chaitman BR, Picard MH, Kwong RY, O’Brien SM, Huang Z, et al. Outcomes in the ISCHEMIA trial based on coronary
Introduction. Contemporary guideline-directed management of patients with chronic coronary disease (CCD) involves both lifestyle and pharmacological interventions, 1 which can
Outcomes in the ISCHEMIA Trial Based on Coronary Artery Disease and Ischemia Severity Circulation , 10.1161/CIRCULATIONAHA.120.049755 , 144 (13) : 1024-1038 , Online
We investigated the relationship between severity of CAD and ischemia and trial outcomes, overall and by management strategy. METHODS: In total, 5179 patients with moderate or
We set out to determine whether estimates of severity of CAD or ischemia were independently associated with increased risk of all-cause mortality, myocardial infarction (MI), or other cardiovascular outcomes in the ISCHEMIA
The present analysis from the ISCHEMIA trial demonstrates that, in patients with chronic coronary artery disease, revascularization with both PCI or CABG was associated with
This study investigates the impact of end-stage renal disease (ESRD) on systemic and localized outcomes in peripheral artery disease (PAD) patients following endovascular
Conclusions: Ischemia severity was not associated with increased risk after adjustment for CAD severity. More severe CAD was associated with increased risk. Invasive
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