Immunotherapy With Rituximab In Follicular Lymphomas
Di: Everly
Follicular lymphoma (FL) is the second most common type of non-Hodgkin’s lymphoma. FL is an incurable disease with treatment options ranging from a “watch-and-wait” approach to localized therapy with radiation or systemic
Rituximab in Follicular Lymphoma: The First Chapter of the New Era?

Non-Hodgkin Lymphomas (NHL) represent a recent and fascinating domain of hemato-oncology, in which remarkable progress has been made. The conventional treatments of indolent
Immunotherapy with rituximab in follicular lymphomas . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter
Obinutuzumab, when combined with chemotherapy, was found to be superior to rituximab-based chemoimmunotherapy in follicular lymphoma and small lymphocytic
Immunotherapy is a treatment technique that targets the immune system, making it work more effectively to fight disease – in this case, cancer. The most common immunotherapy drug used
- Targeted therapies for lymphoma
- Rituximab versus active surveillance in patients with follicular
- Follicular Lymphoma Treatment: What’s the Latest?
Active specific immunotherapy for follicular lymphomas with tumor-derived immunoglobulin idiotype antigen vaccines: Fl and other NHL: Id-KLH vaccine|GM-CSF :
Novel immunotherapy approaches to follicular lymphoma
Rituximab-based immunochemotherapy is now the standard choice for the first-line therapy of FL, followed by rituximab maintenance (RM) in patients with response, which
In a trial including patients with low tumour burden follicular lymphoma, four once-weekly doses of rituximab (first dose intravenous, next three subcutaneous) with rituximab maintenance
6. Morschhauser F, Fowler NH, Feugier P, et al: Rituximab plus lenalidomide in advanced untreated follicular lymphoma. N Engl J Med 379:934-947, 2018. 7. Morschhauser F,
Follicular lymphoma is characterized by stable expression of the CD20 antigen on the tumour cells surface. The anti CD20 antibody Rituximab (Mabthera ®) has shown to be effective in
Conclusion: By elucidating the distinct molecular and immune landscapes of FL at the time of diagnosis and transformation, this study underscores the importance of immune
Approaches restoring local T cell function, e.g., by usage of checkpoint inhibitors has demonstrated clinical activity (ORR 40%) and can achieve long-term remissions. Ongoing trials
These data indicate that patients with follicular NHL who require therapy should now receive rituximab plus chemotherapy as first-line treatment.
Obinutuzumab for the First-Line Treatment of Follicular Lymphoma
Treatment of limited stage follicular lymphoma with Rituximab immunotherapy and involved field radiotherapy in a prospective multicenter Phase II trial-MIR trial Mathias Witzens-Harig1,
Frontline therapy with rituximab added to the combination of cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) significantly improves the outcome for patients with advanced-stage follicular lymphoma
Non-Hodgkin Lymphomas (NHL) represent a recent and fascinating domain of hemato-oncology, in which remarkable progress has been made. The conventional treatments
CB17-SCID mice bearing human follicular DOHH-2 lymphoma were treated once weekly with rituximab (10 mg/kg) or physiological saline over 3 weeks. To obtain the tracer
Follicular lymphoma (FL) is the most frequent indolent lymphoma in the Western world and is characterized in almost all cases by the t(14;18) translocation that results in
Rituximab immunotherapy results in the induction of a lymphoma idiotype-specific T-cell response in patients with follicular lymphoma: support for a ‘vaccinal effect’ of rituximab Blood. 2009; 113
First-line treatment of follicular lymphoma (FL) with golcadamide, rituximab +/- nivolumab: An umbrella randomised phase 2 investigator-led study. Authors : Geoffrey Chong ,
In the last decade, passive immunotherapy with anti-CD20 monoclonal antibody, Rituximab, modified the therapeutic approach of B cell non-Hodgkin lymphoma (NHL) (1, 2). Conventional
Front-line treatment for follicular lymphoma has evolved with the introduction of maintenance therapy, bendamustine (Benda), obinutuzumab (G), and lenalidomide (Len). We
Non-Hodgkin Lymphomas (NHL) represent a recent and fascinating domain of hemato-oncology, in which remarkable progress has been made. The conventional treatments
Results and conclusions: Combining chemotherapy with Rituximab had better results compared to the same chemotherapy, administered alone, both in induction and in case
Purpose: Radioimmunotherapy combines biologic and radiolytic mechanisms to target and destroy tumor cells, thus offering a needed therapeutic alternative for refractory non
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