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Axon Pruning: An Active Role For Glial Cells: Current Biology

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Axonal pruning is a well known developmental program in which axonal outgrowths are eliminated during maturation in a competitive manner in which axonal boutons compete for

Glial Cells - The Definitive Guide | Biology Dictionary

Axon Pruning: An Active Role for Glial Cells: Current Biology

tial role for non-neuronal glial cells in pruning, and several neuron–glia signalling pathways have been identified that are crucial for synaptic maturation7–12. These studies are

Recent work in an invertebrate system suggests an active role for glial cells in the pruning of axons. In the mushroom bodies of the Drosophila brain, glial cells selectively

In this issue of Current Biology, Watts and his colleagues reported ultrastructural analyses showing the involvement of glial cells in the axon pruning of γ neurons [16]. In

The evidence suggests that there are several similarities between the mechanisms that are involved in developmental axon pruning and axon elimination in disease. In summary,

  • Axon Pruning: An Active Role for Glial Cells: Current Biology
  • Axon pruning: an active role for glial cells.
  • Neuron-glia interaction in the insect nervous system

Marmor-Kollet et al. profile Drosophila larval and adult astrocytes to identify astrocytic genes potentially important for neuronal remodeling of mushroom body neurons. Astrocytic Arpc1, a

It is not currently known how particular axon branches are specified for pruning, nor which mammalian cell types engulf pruned axons. In Drosophila, glial cells have a central role

Axon pruning: an active role for glial cells. Axon pruning: an active role for glial cells. Axon pruning: an active role for glial cells Curr Biol. 2004 Apr 20;14(8):R302-4. doi:

Axon pruning: an active role for glial cells

Axon pruning during development is essential for proper wiring of the mature nervous system, but its regulation remains poorly understood. We have identified an

During metamorphosis of Drosophila, selective pruning of larval axons is developmentally regulated by ecdysone and caused by local axon degeneration. Previous studies have revealed intrinsic molecular and cellular

Pruning to refine synaptic networks is a common feature of neural circuit development. New work has shown that, in the Drosophila brain, the steroid hormone ecdysone signals neurons to

There are two obvious possible roles for glia in this pruning process: they could be passive phagocyte scavengers which clean up the debris of intrinsic axonal degeneration; or

In the following review, we discuss our present understanding of the cellular and molecular mechanisms that regulate the pruning of axons during neuronal development as well as in

Developmental axon pruning is widely used in constructing the nervous system. Accordingly, diverse mechanisms are likely employed for various forms of axon pruning [1–7]. In the

Two variations of axon pruning. (A) In small-scale axon terminal pruning, the axon first extends short axon terminal arbors toward cells within the same target area.Later, some of the terminal

Axon Pruning An Active Role for Glial Cells

Axon pruning is involved in establishment and maintenance of functional neural circuits. During metamorphosis of Drosophila, selective pruning of larval axons is

Axon pruning: an active role for glial cells. Coronavirus: Find the latest articles and preprints Sign in or create an account. https://orcid.org. Europe PMC. Menu. About. About

Axon pruning: an active role for glial cells.. Axon pruning: an active role for glial cells. Visit the post for more. Skip to main content. Welcome; Research; People; Microscopy; Publications;

Brain Cells - The Definitive Guide | Biology Dictionary

Several experimental strategies clearly demonstrated an active role for glial cells during axon pruning, independent of axon fragmentation [75••, 76••]. Whereas in normal

Background: Axon pruning is involved in establishment and maintenance of functional neural circuits. During metamorphosis of Drosophila, selective pruning of larval axons is

Allen and Eroglu review the current state of knowledge on the cell biology of astrocyte-synapse interactions and pose some pressing questions that need to be addressed

Glia outnumber neurons and are the most abundant cell type in the nervous system. Whereas neurons are the major carriers, transducers, and processors of information,

The Role of Glia in Developmental Axon Pruning 679 Figure 1. Ultrastructural Time-Course Analy-sis of Axon Pruning (A) Schematic illustration of developmental axon pruning of MB neurons.

Our study reveals a key role for glia in the removal of axon fragments during developmental axon pruning. Axon pruning of Drosophila MB γ neurons occurs through a

Background: Axon pruning is involved in establishment and maintenance of functional neural circuits. During metamorphosis of Drosophila, selective pruning of larval axons is

Our results indicate that glial cells have more active roles during neural reorganization. Although ecdysone-induced stimulation of γ neurons triggers the pruning of