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Antimutagenic Role Of Autonomous 3′ → 5′-Exonucleases

Di: Everly

Original and published data on the antimutagenic role of autonomous 3 5-exonucleases (AE) are analyzed. AE are not bound covalently to DNA polymerases but are often involved in

In this work, we have shown that the autonomous 3′→5′ exonucleases from rat liver, calf thymus and Escherichia coli can proofread for the DNA polymerase β from rat liver in

[Related to DNA polymerases and individual 3′–>5

Substrate preferences of hWRN and mWRN 3′→5′ exonucleases. (A–F ...

In the present work, activities of 3′ → 5′-exonucleases and DNA polymerases are studied in extracts of rodents and human normal and cancer cells and, for the first time, their

Our own and literary data about antimutagenic role of autonomous 3′–>5′-exonucleases (AE) are analyzed. AE are not bound covalently to DNA polymerases but often involved in replicative

Recently we have revealed a high content of autonomous 3″→5″ exonucleases (AE), i.e., those not bound covalently with DNA polymerases, in cells of vertebrates, from fish to human [1]. In

  • Antimutagenic Role of Autonomous 3′ → 5′-Exonucleases
  • DNA Polymerase-associated and autonomous vertebrate 3′→5
  • Properties of autonomous 3′–>5′ exonucleases

PDF | „Editing“ 3′—-5′ exonuclease activity of DNA polymerases corrects replication errors. This activity associated with procaryotic DNA polymerases | Find, read and cite all the research

Europe PMC is an archive of life sciences journal literature.

Mutations in genes of DNA polymerases or corrective 3′ → 5′-exonucleases lead to a decrease in the fidelity of DNA biosynthesis throughout the genome, which is accompanied

Antimutagenic role of autonomous 3′→5′-exonucleases

Our own and literary data about antimutagenic role of autonomous 3′–>5′-exonucleases (AE) are analyzed. AE are not bound covalently to DNA polymerases but often involved in replicative

Europe PMC is an archive of life sciences journal literature.

Autonomous 3′→5′ exonucleases (AE) are not bound covalently to DNA polymerases, but they are often included into the replicative complexes. Intracellular AE

‘autonomous 3 ′–5′ exonucleases’(see below) — might help in different cases of genotoxic stress. Mutator phenotypes (with the potential for cancer progression4) have been described in

Original and published data on the antimutagenic role of autonomous 3 5-exonucleases (AE) are analyzed. AE are not bound covalently to DNA polymerases but are often involved in

Our own and literary data about antimutagenic role of autonomous 3′–>5′-exonucleases (AE) are analyzed. AE are not bound covalently to DNA polymerases but often involved in replicative

  • The Correcting Role of Autonomous 3" → 5" Exonucleases
  • Complex of repair DNA polymerase β with autonomous 3′→5
  • [Related to DNA polymerases and individual 3′–>5
  • Properties of autonomous 3′→5′ exonucleases
  • Antimutagenic role of autonomous 3′→5′-exonucleases

The Correcting Role of Autonomous 3" → 5" Exonucleases

The enzyme activity of autonomous 3′→5′-exonucleases (AE) has been established to be 25–90% of the total 3′→5′ exonuclease activity of the extracts. A part of the AE is revealed in a zone of

Autonomous 3′-45′- exonucleases (AE) are not bound covalently to DNA polymerases but often are included in rep- licative complexes [2]. The antimutagenic role of AE in vivo has been

Europe PMC is an archive of life sciences journal literature.

A study was made of the correcting role of autonomous 3′–>5′ exonucleases (AE) contained in multienzyme DNA polymerase complexes of rat hepatocytes or calf thymocytes. DNA was

Autonomous 3′→5′ exonucleases have a corrective function, but after transition into cytoplasm these enzymes destroy aberrant DNA that appears during replication and

A study was made of the correcting role of autonomous 3″ → 5″ exonucleases (AE) contained in multienzyme DNA polymerase complexes of rat hepatocytes or calf thymocytes. DNA was

Two 3′–>5′ exonucleases of 40 kDa and 50 kDa (exo-40 and exo-5) have been isolated from rat liver nuclei and purified to near homogeneity. They are shown to excise mismatched

Complex of repair DNA polymerase β with autonomous 3′→5

A study was made of the correcting role of autonomous 3′–>5′ exonucleases (AE) contained in multienzyme DNA polymerase complexes of rat hepatocytes or calf thymocytes. DNA was

Request PDF | On Mar 1, 2002, N L Ronzhina and others published [Associated with DNA polymerases and autonomic 3′-5′-exonucleases from invertebrates, protozoa and bacteria] |

DNA Polymerase-Associated and Autonomous 3’→ 5’ Exonucleases in Invertebrates, Unicellulars, and Bacteria N. L. Ronzhina, N. V. Belyakova, T. P. Kravetskaya, and V. M.

The fidelity of these polymerases is increased by the PE function of DNA polymerases δ and ε, as well as autonomous 3′ → 5′ exonucleases, which are widespread over the entire phylogenetic

Volume 38, issue 5 articles listing for Molecular Biology. Skip to main content. Menu. Find a journal Publish with us Track your research Search. Cart. Home. Molecular Biology. Volumes

The fidelity of these polymerases is increased by the PE function of DNA polymerases δ and ε, as well as autonomous 3′ → 5′ exonucleases, which are widespread over the entire phylogenetic

The nonprocessive, autonomous nature of the TREX exonucleases led to the suggestion that these enzymes might serve as proofreading exonucleases for the nuclease

Over the past few years, several new 3′ 5′ exonucleases have been identified. In vitro studies of these enzymes have uncovered much about their potential functions in vivo, and certain